Hydrochloric Acid → HCID 131711513, compound

HRID 263227Notes

Reaction equation

HRID 263227 reaction equation
[CH3:1][N:2]([CH3:16])[CH2:3][CH2:4][C@@H:5]1[CH2:14][C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH2:7][C@H:6]1[OH:15].[ClH:17]>CCOCC>[ClH:17].[CH3:16][N:2]([CH3:1])[CH2:3][CH2:4][C@@H:5]1[CH2:14][C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH2:7][C@H:6]1[OH:15]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 70608476HCID 70608476, compound

Product 1

HCID 131711513HCID 131711513, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A cooled solution of 1.7 g of the above oil of Example 10 in ether is treated with excess hydrogen chloride saturated isopropaneol, and the resulting solid filtered off and recrystallized from isopropanol to give the title compound, m.p. 166°-169°.

Workup

  1. filtrationthe resulting solid filtered off
  2. customrecrystallized from isopropanol

Sources & evidence

ORD record
ord-0848a1d182a94fb088c2a3f5c4849384
Source dataset
uspto-grants-1979_05
Patent number
US04156723

Reaction notes

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