Methylamine → 1-Methylamino-1-[2-(4-methoxy-2-pyridylmethylthio)ethylamino]-2-nitroethylene

HRID 263252Notes

Reaction equation

HRID 263252 reaction equation
[CH3:1][NH2:2].O.CS[C:6]([NH:11][CH2:12][CH2:13][S:14][CH2:15][C:16]1[CH:21]=[C:20]([O:22][CH3:23])[CH:19]=[CH:18][N:17]=1)=[CH:7][N+:8]([O-:10])=[O:9]>C(O)C>[CH3:1][NH:2][C:6]([NH:11][CH2:12][CH2:13][S:14][CH2:15][C:16]1[CH:21]=[C:20]([O:22][CH3:23])[CH:19]=[CH:18][N:17]=1)=[CH:7][N+:8]([O-:10])=[O:9]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 70509356HCID 70509356, compound

Product 1

HCID 705091601-Methylamino-1-[2-(4-methoxy-2-pyridylmethylthio)ethylamino]-2-nitroethylene

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Methylamine in ethanol (33%, 20 cc) was added to 1-methylthio-1-[2-(4-methoxy-2-pyridylmethylthio)ethylamino]-2-nitroethylene monohydrate (2.01 g) and the mixture was stirred at 18° for 20 minutes and evaporated to an oil which was crystallised from propan-2-ol to give the title product (1.1 g) m.p. 107°-108.5°.

Workup

  1. customevaporated to an oil which
  2. customwas crystallised from propan-2-ol

Sources & evidence

ORD record
ord-71dd6ff9403e44b7bf1a3d521e766adc
Source dataset
uspto-grants-1979_05
Patent number
US04156727

Reaction notes

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