3-(Aminosulfonyl)-4-chlorobenzoyl chloride → HCID 21316568, compound

HRID 263286Notes

Reaction equation

HRID 263286 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=1[S:11](=[O:14])(=[O:13])[NH2:12].[CH2:15]([C:17]1[O:21][C:20]2[CH:22]=[CH:23][C:24]([CH3:26])=[CH:25][C:19]=2[CH:18]=1)[CH3:16].[Cl-].[Al+3].[Cl-].[Cl-]>CO>[CH2:15]([C:17]1[O:21][C:20]2[CH:22]=[CH:23][C:24]([CH3:26])=[CH:25][C:19]=2[C:18]=1[C:6](=[O:7])[C:5]1[CH:9]=[CH:10][C:2]([Cl:1])=[C:3]([S:11](=[O:14])(=[O:13])[NH2:12])[CH:4]=1)[CH3:16]

Participants

5

Reactant 3

HCID 30179793-(Aminosulfonyl)-4-chlorobenzoyl chlorideHCID 6451240Aluminum(III) ChlorideHCID 124165062-Ethyl-5-methyl-1-benzofuran

Product 1

HCID 21316568HCID 21316568, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

is obtained as described in Example 1 from 10 g 4-chloro-3-sulfamoylbenzoyl chloride and 6.2 g 2-ethyl-5-methylbenzo[b]furan in the presence of 11.4 g aluminum chloride. Colorless crystals, m.p. 147°-150° C. (from methanol).

Workup

  1. customis obtained

Sources & evidence

ORD record
ord-39cb351c2e9f4aa99473c5ae071b218f
Source dataset
uspto-grants-1979_05
Patent number
US04156732

Reaction notes

Loading…