HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
o-Vanillin → 2-(4-Chloro-3-nitrobenzoyl)-7-methoxybenzo[b]furan
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | o-Vanillin | HCID 8991 | — |
| Edukt | Potassium Hydroxide | HCID 14797 | — |
| Edukt | 2-Bromo-1-(4-chloro-3-nitrophenyl)ethan-1-one | HCID 2778330 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 2-(4-Chloro-3-nitrobenzoyl)-7-methoxybenzo[b]furan | HCID 21316572 | — |
Reaktionsschritte
2 g KOH are dissolved in 50 ml methanol, a solution of 5.4 g 2-hydroxy-3-methoxybenzaldehyde is added and subsequently a suspension of 10 g 2-bromo-4'-chloro-3'-nitroacetophenone in 75 ml methanol. The batch is refluxed for 6 hours, agitation is continued overnight at room temperature, and the crystals are suction-filtered. M.p. 136° C. (from ethyl acetate).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04156732 |
| Quelldatensatz | uspto-grants-1979_05 |
| ORD ID | ord-7d340f095cd9431785b78c7db3008a04 |
| Quellennotiz | uspto-grants-1979_05 |