Hydrochloric Acid → HCID 21316937, compound

HRID 263306Notes

Reaction equation

HRID 263306 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1[N+:10]([O-:12])=[O:11].[ClH:13].[CH3:14][O:15][CH2:16][CH2:17][OH:18]>>[ClH:13].[CH3:14][O:15][CH2:16][CH2:17][O:18][C:6](=[NH:7])[C:5]1[CH:8]=[CH:9][C:2]([NH2:1])=[C:3]([N+:10]([O-:12])=[O:11])[CH:4]=1

Participants

4

Reactant 3

HCID 313Hydrochloric Acid2×HCID 80192-MethoxyethanolHCID 5959014-Amino-3-nitrobenzonitrile

Product 1

HCID 21316937HCID 21316937, compound

Procedure

100 g of 4-amino-3-nitrobenzonitrile are suspended in 500 ml of 2-methoxyethanol. Gaseous hydrochloric acid is introduced, the temperature of the solution is allowed to rise to 70° C. in the course of the introduction, and the solution is maintained at this temperature by cooling until it decreases by itself. Finally, the solution is cooled to 0°-5° C., saturated with gaseous hydrochloric acid and allowed to stand overnight. The precipitate is then filtered off with suction, washed with isopropanol and dried over KOH in a desiccator.

Workup

  1. customto rise to 70° C. in the course of the introduction
  2. temperaturethe solution is maintained at this temperature
  3. temperatureby cooling until it
  4. filtrationThe precipitate is then filtered off with suction
  5. washwashed with isopropanol
  6. dry with materialdried over KOH in a desiccator

Sources & evidence

ORD record
ord-f02b143f89e24d14964d25810d370398
Source dataset
uspto-grants-1979_05
Patent number
US04156778

Reaction notes

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