Sodium Iodide → HCID 10448329, compound

Participants

Reaction Steps

To a 250 mL round-bottomed flask equipped with condenser and N2 inlet were added 13.9 g (39.4 mmol) 2-(cyclohexyl)-2-phenylethanol tosylate, 80 mL acetone and 6.49 g (43.3 mmol) sodium iodide. The reaction was refluxed 36 hr, cooled, and evaporated. The residue was taken up in ethyl acetate, washed with water and aqueous sodium bisulfite solution, dried over sodium sulfate, and evaporated to an oil, 12.11 g (98%), which was used directly in the next step.

Provenance & Evidence