Potassium Bromide → HCID 67716095, compound

HRID 263752Notes

Reaction equation

[CH3:1][C@@:2]1(/[CH:28]=[C:29]2/[C:30](=[O:39])[N:31]([CH2:34][C:35]([F:38])([F:37])[F:36])[CH2:32][CH2:33]/2)[S:8](=[O:10])(=[O:9])[C@H:7]2[N:4]([C:5](=[O:11])[CH2:6]2)[C@H:3]1[C:12]([O:14]C(C1C=CC=CC=1)C1C=CC=CC=1)=[O:13].[K+].[Br-]>>[CH3:1][C@@:2]1(/[CH:28]=[C:29]2/[C:30](=[O:39])[N:31]([CH2:34][C:35]([F:38])([F:37])[F:36])[CH2:32][CH2:33]/2)[S:8](=[O:10])(=[O:9])[C@H:7]2[N:4]([C:5](=[O:11])[CH2:6]2)[C@H:3]1[C:12]([OH:14])=[O:13]

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 86751026HCID 86751026, compound

Product 1

HCID 67716095HCID 67716095, compound

Procedure

192 mg (0.34 mmol) of benzhydryl (E)-(2S,3S,5R)-3-methyl-3-[2-oxo-1-(2,2,2-trifluoro-ethyl)-pyrrolidin-3-ylidenemethyl]-4,4,7-trioxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylate were deprotected analogously to Example 11. Yield: 78 mg (59%) of colorless crystal powder MS: (M+NH4)+ 414.4 IR (KBr): 2800(br), 1790, 1729, 1674, 1646, 1321, 1166 cm-1

Sources & evidence

ORD record: ord-330b956788e240bea5e3943d0a6d8e03
Source dataset: uspto-grants-1997_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05644053

Reaction notes

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