HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 22874283, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 70088514 | HCID 70088514 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | HCID 22874283 | HCID 22874283 | — |
Reaction Steps
Analogously to Example 1 i), 1.05 g of 5(S)-[1(S)-(Boc-amino)-2-(p-fluorophenyl)ethyl]-3(R)-(p-trifluoromethylphenylmethyl)-dihydrofuran-2-(3H)-one in 35.5 ml of dimethoxyethane and 17.9 ml of water are hydrolysed with 8.7 ml of 1 M lithium hydroxide solution to form the title compound which is used further directly.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05643878 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-5e1e06fb018d4844a8a34e56bb08e06e |
| Source note | uspto-grants-1997_07 |