6-Bromo-1-hexanol → 12-Bromododecyl prop-2-enoate

HRID 263828Notes

Reaction equation

HRID 263828 reaction equation
FC1C(F)=CC=CC=1C1C=C[C:12]([O:15]CCCCCCOC(=O)C=C)=[CH:11][CH:10]=1.[Br:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][OH:40].BrCCCCCCO>>[C:12]([O:40][CH2:39][CH2:38][CH2:37][CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][Br:27])(=[O:15])[CH:11]=[CH2:10]

Participants

4

Reactant 3

HCID 779706-Bromo-1-hexanolHCID 13789512-Bromo-1-dodecanolHCID 214594982,3-Difluoro-4'-[6-(acryloyloxy)hexyloxy]biphenyl

Product 1

HCID 1384139712-Bromododecyl prop-2-enoateYield 75.1%

Procedure

The same procedure as in the synthesis (a) of Example 2 was repeated except that 44.0 g of 12-bromo-1-dodecanol were used instead of 30 g of 6-bromo-1-hexanol to give 39.8 g (Y., 75.1%) of 12-bromododecyl acrylate.

Sources & evidence

ORD record
ord-5b5dcec9ed9f4ca092e9d375ad46bed9
Source dataset
uspto-grants-1997_07
Patent number
US05645760

Reaction notes

Loading…