HRID263941

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID78491

1-Butanol, 4-bromo-, 1-acetate

C6H11BrO2

HCID5271882

6-Chloro-N-phenyl-1,3-dihydro-2H-purin-2-imine

C11H8ClN5

PRODUCTS

生成物

结构：CC(=O)OCCCCn1cnc2c(Cl)nc(Nc3ccccc3)nc21

HCID385891

未命名化合物

收率 45%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID21754633

未命名化合物

PROCEDURE

实验过程

Reaction between 2-anilino-6-chloropurine and 4-acetoxybutyl bromide was performed as described in A.a., above, giving 2-anilino-6-chloro-9-(4-acetoxybutyl) purine in a 45% yield (from DMF/chloroform), mp 195°-197° C. 1H NMR δ9.98 (s, 2-NH), 8.32 (s, 8-H), 7.31 (m, C6H5), 4.20 (t, 1'-CH2), 4.02 (t, 4'-CH2), 1.95 (s, CH3), 1.92, 1.58 (m, 2'/3'CH2).