戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 263941作成日：2026年10月25日

1-Butanol, 4-bromo-, 1-acetate → 4-(2-Anilino-6-chloro-9H-purin-9-yl)butyl acetate

https://huagongshe.com/reaction/263941

反応式

関与物質

役割名称HCID仕込み量
反応物1-Butanol, 4-bromo-, 1-acetateHCID 78491—
反応物9H-Purin-2-amine, 6-chloro-N-phenyl-HCID 5271882—
溶媒chloroform N,N-dimethylformamideHCID 21754633—
生成物4-(2-Anilino-6-chloro-9H-purin-9-yl)butyl acetateHCID 38589145%

反応手順

Reaction between 2-anilino-6-chloropurine and 4-acetoxybutyl bromide was performed as described in A.a., above, giving 2-anilino-6-chloro-9-(4-acetoxybutyl) purine in a 45% yield (from DMF/chloroform), mp 195°-197° C. 1H NMR δ9.98 (s, 2-NH), 8.32 (s, 8-H), 7.31 (m, C6H5), 4.20 (t, 1'-CH2), 4.02 (t, 4'-CH2), 1.95 (s, CH3), 1.92, 1.58 (m, 2'/3'CH2).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05646155
出典データセットuspto-grants-1997_07
ORD IDord-ac9a61d7a1d2420ebcca417076648ca9
出典メモuspto-grants-1997_07