Phenacyl bromide → HCID 8833768, compound

HRID 263968Notes

Reaction equation

HRID 263968 reaction equation
Br[CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:4].O=C(C)C[O:14][C:15]1[CH:16]=[CH:17][CH:18]=[C:19]2[C:24]=1[N:23]=[CH:22][CH:21]=[CH:20]2>>[O:4]=[C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH2:2][O:14][C:15]1[CH:16]=[CH:17][CH:18]=[C:19]2[C:24]=1[N:23]=[CH:22][CH:21]=[CH:20]2

Participants

3

Reactant 2

HCID 6259Phenacyl bromideHCID 15269575HCID 15269575, compound

Product 1

HCID 8833768HCID 8833768, compoundYield 69%

Procedure

8-(2-Oxo-2-phenylethoxy)quinoline (8a) was prepared from 2-bromoacetophenone by the same procedure as 7a in 69% yield. mp: 124°-125° C.; 1H-NMR (CDCl3): δ5.65 (s, 2H, OCH2), 6.95-8.97 (m, 11H, Ar--H).

Sources & evidence

ORD record
ord-cbc21911afcb4d77adf08157d562ba3e
Source dataset
uspto-grants-1997_07
Patent number
US05646164

Reaction notes

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