HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenacyl bromide → 2-Methyl-8-(2-oxo-2-phenylethoxy)quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenacyl bromide | HCID 6259 | — |
| Reactant | 2-Methyl-8-(2-oxopropoxy)quinoline | HCID 10727414 | — |
| Product | 2-Methyl-8-(2-oxo-2-phenylethoxy)quinoline | HCID 10707666 | 72% |
Reaction Steps
2-Methyl-8-(2-oxo-2-phenylethoxy)quinoline (11a) was prepared from 2-bromoacetophenone by the same procedure as 10a in 72% yield. mp: 70°-71° C.; 1H-NMR (CDCl3): δ2.77 (s, 3H, 2-CH3), 5.63 (s, 2H, OCH2), 6.94-8.10 (m, 8H, Ar--H), 7.29 (d, 1H, 3-H), 7.99 (d, 1H, 4-H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05646164 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-30c6e40533fd425799b94b5a78bfb9c5 |
| Source note | uspto-grants-1997_07 |