反应详情

2-Methyl-8-(2-oxo-2-phenylethoxy)quinoline (11a) was prepared from 2-bromoacetophenone by the same procedure as 10a in 72% yield. mp: 70°-71° C.; 1H-NMR (CDCl3): δ2.77 (s, 3H, 2-CH3), 5.63 (s, 2H, OCH2), 6.94-8.10 (m, 8H, Ar--H), 7.29 (d, 1H, 3-H), 7.99 (d, 1H, 4-H).