Hydrochloric Acid → HCID 23330806, compound

HRID 26400Notes

Reaction equation

HRID 26400 reaction equation
[CH2:1]([C:4]1([CH2:20][CH2:21][NH:22][CH2:23][CH:24]2[CH2:27][CH2:26][CH2:25]2)[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([O:14][CH3:15])[CH:12]=2)[CH2:7][CH2:6][C:5]21OCCO2)[CH:2]=[CH2:3].Cl>C(O)C>[CH2:1]([C:4]12[C:13]3[CH:12]=[C:11]([O:14][CH3:15])[CH:10]=[CH:9][C:8]=3[CH2:7][CH:6]=[C:5]1[N:22]([CH2:23][CH:24]1[CH2:25][CH2:26][CH2:27]1)[CH2:21][CH2:20]2)[CH:2]=[CH2:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 23330786HCID 23330786, compound

Product 1

HCID 23330806HCID 23330806, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Preparation From 1-allyl-1-[2-(N-cyclobutylmethylamino)ethyl]-2,2-ethylenedioxy-7-methoxy-1,2,3,4-tetrahydronaphthalene (XIXb). Compound XIXb (33.7 g) treated with hydrochloric acid in aqueous ethanol according to Example 39(b) afforded 27.5 g (98%) IIf identical with the material obtained in Example 40(a) above.

Sources & evidence

ORD record
ord-7a8ba54f4f254a49ae51ef943d29cc18
Source dataset
uspto-grants-1979_04
Patent number
US04150032

Reaction notes

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