反应详情

35.25 g of 5-methoxy-1-tetralone and 61 ml of N,N-dimethylhydrazine were heated to about 80° under argon for 5 hours. The mixture was left to cool, 200 ml of 10% sodium chloride solution were added and the mixture was extracted several times with diethyl ether. The mixture was dried over sodium sulfate, filtered and evaporated. The oily residue was distilled over a 10 cm Vigreux column. At 85°-95°/0.1 mbar there were obtained 36.4 g (83%) of 5-methoxy-1-tetralone N,N-dimethylhydrazone as a yellow oil.

1. waitThe mixture was left
2. temperatureto cool
3. extractionthe mixture was extracted several times with diethyl ether
4. dry with materialThe mixture was dried over sodium sulfate
5. filtrationfiltered
6. customevaporated
7. distillationThe oily residue was distilled over a 10 cm Vigreux column