反应详情

Aluminum trichloride (6.2 g, 46.5 mmol) was suspended in 50 ml of dichloroethane, and 3.02 g (30.2 mmol) of succinic anhydride and 4.0 g (23.2 mmol) of 2-fluorobiphenyl were added thereto, followed by stirring the mixture at room temperature for 4 hours. The reaction solution was poured in hydrochloric acid containing ice, and extracted with chloroform. The organic layer was washed with water, and dried over anhydrous magnesium sulfate. After the solvent was distilled off under reduced pressure, the residue was recrystallized from chloroform to obtain 5.6 g of the above-mentioned compound (yield 89%).

1. additioncontaining ice
2. extractionextracted with chloroform
3. washThe organic layer was washed with water
4. dry with materialdried over anhydrous magnesium sulfate
5. distillationAfter the solvent was distilled off under reduced pressure
6. customthe residue was recrystallized from chloroform