HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 2,2-bisfluoromethyl-6-nitro-2H-1-benzopyran-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 4-cyano-2,2-bisfluoromethyl-6-nitro-2H-1-benzopyran | HCID 21194980 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2,2-bisfluoromethyl-6-nitro-2H-1-benzopyran-4-carboxylic acid | HCID 21194987 | — |
Reaction Steps
A mixture of 0.93 g of 2,2-bisfluoromethyl-6-nitro-2H-1-benzopyran-4-carbonitrile, 20 ml of acetic acid, 10 ml of water and 10 ml of sulfuric acid was heated while refluxing for 4.5 hours. The reaction mixture was poured into ice-water, and the precipitated crystals were separated by filtration to obtain 0.83 g of 2,2-bisfluoromethyl-6-nitro-2H-1-benzopyran-4-carboxylic acid having a melting point of 171°-172° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05646310 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-02fc2eedf5a843b1a39567c46572dae9 |
| Source note | uspto-grants-1997_07 |