HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2,2-bis(fluoromethyl)-6-trifluoromethyl-2H-1-benzopyran-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | ethyl 2,2-bisfluoromethyl-6-trifluoromethyl-2H-1-benzopyran-4-carboxylate | HCID 19037095 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2,2-bis(fluoromethyl)-6-trifluoromethyl-2H-1-benzopyran-4-carboxylic acid | HCID 9879640 | 92% |
Reaction Steps
A mixture of 0.51 g of 2,2-bis(fluoromethyl)-6-trifluoromethyl-2H-1-benzopyran-4-carboxylic acid ethyl ester, 0.13 g of potassium hydroxide and 10 ml of ethyl alcohol was stirred at room temperature for 2 hours. To the reaction mixture was added ice water and hydrochloric acid and crystals separated out were filtered to obtain 0.43 g of 2,2-bis(fluoromethyl)-6-trifluoromethyl-2H-1-benzopyran-4-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05646308 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-a51aa7638b0e453fbbcd1c8ef96b1368 |
| Source note | uspto-grants-1997_07 |