Hydrochloric Acid → HCID 19037000, compound

HRID 264860Notes

Reaction equation

HRID 264860 reaction equation
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][C:9]([CH2:13][F:14])([CH2:11][F:12])[CH:8]=[C:7]([C:15]([NH:17][CH2:18][CH2:19][C:20]#[N:21])=[O:16])[C:6]=2[CH:22]=1.[ClH:23]>CO>[ClH:23].[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][C:9]([CH2:11][F:12])([CH2:13][F:14])[CH:8]=[C:7]([C:15]([NH:17][CH2:18][CH2:19][C:20]#[N:21])=[O:16])[C:6]=2[CH:22]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19037001HCID 19037001, compound

Product 1

HCID 19037000HCID 19037000, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To 0.34 g of 6-amino-N-(2-cyanoethyl)-2,2-bis-(fluoromethyl)-2H-1-benzopyran-4-carboxamide were added methyl alcohol and a small amount of concentrated hydrochloric acid. The mixture was condensed under reduced pressure to obtain 0.35 g of 6-amino-N-(2-cyanoethyl)-2,2-bis(fluoromethyl)-2H-1-benzopyran-4-carboxamide hydrochloride with a melting point of 202°-205° C.

Workup

  1. customcondensed under reduced pressure

Sources & evidence

ORD record
ord-22613cd4b72a4ba5b511de3dc50ccefd
Source dataset
uspto-grants-1997_07
Patent number
US05646308

Reaction notes

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