HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 264960Generated: November 1, 2026
Hydrochloric Acid → N,N-Dimethyl-L-valinamide--hydrogen chloride (1/1)
https://huagongshe.com/reaction/264960
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 10944665 | HCID 10944665 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | N,N-Dimethyl-L-valinamide--hydrogen chloride (1/1) | HCID 56831841 | — |
Reaction Steps
0.85 g of 2(S)-tert-butoxycarbonylamino-3-methylbutanoic acid (N,N-dimethyl)amide is dissolved in 10 ml of 4N hydrochloric acid in dioxane at 0° C. and stirred for 7 hours at 0° C. The reaction mixture is lyophilised and the title compound is obtained: Rf (ethyl acetate/methanol/conc. ammonia=80:15:5)=0.23.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05646143 |
|---|
| Source dataset | uspto-grants-1997_07 |
|---|
| ORD ID | ord-dc1be2782fea4b6e91295f3b5435e2f2 |
|---|
| Source note | uspto-grants-1997_07 |
|---|
