Potassium Hydroxide → HCID 21323498, compound

HRID 26498Notes

Reaction equation

HRID 26498 reaction equation
CS[C:3]1[N:12]2[C:6]([CH:7]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[C:8]3[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=3[CH:10]=[CH:11]2)=[N:5][N:4]=1.[OH-:23].[K+]>>[C:17]1([CH:7]2[C:8]3[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=3[CH:10]=[CH:11][N:12]3[C:3](=[O:23])[NH:4][N:5]=[C:6]23)[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 14797Potassium HydroxideHCID 213234263-Methylthio-11-phenyl-11H-s-triazolo[3,4-b][3]benzazepine

Product 1

HCID 21323498HCID 21323498, compound

Procedure

3-Methylthio-11-phenyl-11H-s-triazolo[3,4-b][3]benzazepine was treated with potassium hydroxide and the reaction mixture was treated as described. This procedure provided 2,11-dihydro-11-phenyl-3H-s-triazolo[3,4-b][3]benzazepin-3-one as crystals. Colorless needles (as recrystallized from methanol), m.p. 258°-260° C.

Workup

  1. additionthe reaction mixture was treated

Sources & evidence

ORD record
ord-5e696d5e7c8a4ba58ff09d9a8575e82b
Source dataset
uspto-grants-1979_04
Patent number
US04150139

Reaction notes

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