m-Chloroperbenzoic acid → 3-(N-Isopropyl-N-n-propylamino)-5-phenyl-1-oxothiochroman

HRID 264999Notes

Reaction equation

HRID 264999 reaction equation
Cl.[CH:2]([N:5]([CH:9]1[CH2:18][C:17]2[C:12](=[CH:13][CH:14]=[CH:15][C:16]=2[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[S:11][CH2:10]1)[CH2:6][CH2:7][CH3:8])([CH3:4])[CH3:3].ClC1C=CC=C(C(OO)=[O:33])C=1>C(Cl)(Cl)Cl>[CH:2]([N:5]([CH:9]1[CH2:18][C:17]2[C:12](=[CH:13][CH:14]=[CH:15][C:16]=2[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[S:11](=[O:33])[CH2:10]1)[CH2:6][CH2:7][CH3:8])([CH3:3])[CH3:4]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 190280873-(N-Isopropyl-N-n-propylamino)-5-phenylthiochroman hydrochloride

Product 1

HCID 190281483-(N-Isopropyl-N-n-propylamino)-5-phenyl-1-oxothiochroman

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

3-(N-Isopropyl-N-n-propylamino)-5-phenylthiochroman hydrochloride (310 mg, 0.86 mmol) was dissolved in 6 mL chloroform and to the cooled solution (ice-bath) was m-chloroperbenzoic acid (348 mg, 1.72 mmol) added in one portion.

Workup

  1. additionadded in one portion

Sources & evidence

ORD record
ord-ecbfc2937226489c8b1e7ad6cf6a449a
Source dataset
uspto-grants-1997_07
Patent number
US05646309

Reaction notes

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