HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3,4-Difluorophenyl)-1-propanone → 2-Bromo-1-(3,4-difluorophenyl)propan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3,4-Difluorophenyl)-1-propanone | HCID 520050 | — |
| Reactant | 1,4-Dioxane dibromide | HCID 22225919 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-Bromo-1-(3,4-difluorophenyl)propan-1-one | HCID 15281274 | 98.9% |
Reaction Steps
To 3',4'-difluoropropiophenone (Alfa Products, Danvers, Mass. 01923) (90.5 g, 0.53 mole) was added a solution of dioxane dibromide (131 4 g, 0.53 mole) in dioxane (500 ml). The reaction was worked up as in Example 1 to yield crude 2-bromo-3',4'-difluoropropiophenone (130.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05648347 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-8081e874fe1d4a1aa24c39bb080b92b2 |
| Source note | uspto-grants-1997_07 |