Water → HCID 19082160, compound

HRID 265287Notes

Reaction equation

HRID 265287 reaction equation
S([O-])(O[O-])(=O)=O.[K+].[K+].[CH3:9][O:10][C:11]1[C:16]2[NH:17][C:18](=[O:20])[S:19][C:15]=2[C:14]([CH2:21][CH2:22][NH:23][C:24](=[O:40])[CH2:25][CH2:26][S:27][CH2:28][C:29](=[O:39])[NH:30][CH2:31][CH2:32][C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)=[CH:13][CH:12]=1.[OH2:41].C[OH:43].O>>[CH3:9][O:10][C:11]1[C:16]2[NH:17][C:18](=[O:20])[S:19][C:15]=2[C:14]([CH2:21][CH2:22][NH:23][C:24](=[O:40])[CH2:25][CH2:26][S:27]([CH2:28][C:29](=[O:39])[NH:30][CH2:31][CH2:32][C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)(=[O:43])=[O:41])=[CH:13][CH:12]=1

Participants

5

Reactant 4

HCID 962WaterHCID 10313463Potassium peroxymonosulphateHCID 19082247HCID 19082247, compoundHCID 22242641Methanol--water (1/1)

Product 1

HCID 19082160HCID 19082160, compound

Procedure

Potassium peroxymonosulphate (5.57 g) was gradually added to a solution of the compound from step c) (2.81 g) in methanol:water (6:4, 72 ml) cooled to 0°. The mixture was stirred for 4 hours, water added and the whole extracted with chloroform. A yellow solid precipitated from the aqueous layer and was removed by filtration, and washed (water and pentane) to give the subtitled compound.

Workup

  1. temperaturecooled to 0°
  2. extractionthe whole extracted with chloroform
  3. customA yellow solid precipitated from the aqueous layer
  4. customwas removed by filtration
  5. washwashed (water and pentane)

Sources & evidence

ORD record
ord-54156872703f46a8b2fd708eb8ff62c2
Source dataset
uspto-grants-1997_07
Patent number
US05648370

Reaction notes

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