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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 265290Generated: October 29, 2026

7-(2-Aminoethyl)-4-hydroxy-1,3-benzothiazol-2(3H)-one hydrobromide → 2,2-Difluoro-N-[2-[4-hydroxy-2-oxo-3H-1,3-benzothiazol-7-yl]ethyl]-6-[2-phenylethoxy]hexanamide

https://huagongshe.com/reaction/265290

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-(2-Aminoethyl)-4-hydroxy-1,3-benzothiazol-2(3H)-one hydrobromideHCID 13814270—
Reactant2,2-Difluoro-6-[2-phenylethoxy]hexanoic acidHCID 19082214—
Product2,2-Difluoro-N-[2-[4-hydroxy-2-oxo-3H-1,3-benzothiazol-7-yl]ethyl]-6-[2-phenylethoxy]hexanamideHCID 19082199—

Reaction Steps

The subtitled compound was prepared by the method outlined in Example 15a) using the material from step c) and 7-[2-aminoethyl]-4-hydroxy-1,3-benzothiazol-2(3H)-one hydrobromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05648370
Source datasetuspto-grants-1997_07
ORD IDord-b1e593c6318547cd8708df32f080c44e
Source noteuspto-grants-1997_07