Sodium Methoxide → 3-methoxy-11-methyl-11H-s-triazolo[3,4-b][3] benzazepine

HRID 26532Notes

Reaction equation

[CH3:1][CH:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH:6]=[CH:5][N:4]2[C:13](S(C)(=O)=O)=[N:14][N:15]=[C:3]12.[CH3:20][O-:21].[Na+]>>[CH3:20][O:21][C:13]1[N:4]2[C:3]([CH:2]([CH3:1])[C:8]3[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=3[CH:6]=[CH:5]2)=[N:15][N:14]=1

Participants

Reactant 2

HCID 10942334Sodium Methoxide

HCID 21323329HCID 21323329, compound

Product 1

HCID 213233203-methoxy-11-methyl-11H-s-triazolo[3,4-b][3] benzazepine

Procedure

The reaction of 11-methyl-3-methylsulfonyl-11H-s-triazolo[3,4-b][3]benzazepine with sodium methoxide yielded 3-methoxy-11-methyl-11H-s-triazolo[3,4-b][3] benzazepine. Colorless prisms (as recrystallized from ether), melting point: 101°-102° C.

Sources & evidence

ORD record: ord-c8593d6452b74e0ca7d2f74bd483df45
Source dataset: uspto-grants-1979_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04150139

Reaction notes

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