4-Phenylsemicarbazide hydrochloride → 2-Oximino-1-(4-phenyl semicarbazono)-3-indanone

HRID 265346Notes

Reaction equation

HRID 265346 reaction equation
Cl.[C:2]1([NH:8][C:9](=[O:12])[NH:10][NH2:11])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N:13](=[C:15]1[C:23](=O)[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[C:16]1=[O:25])[OH:14]>O.C(O)C>[N:13](=[C:15]1[C:16](=[O:25])[C:17]2[C:22](=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:23]1=[N:11][NH:10][C:9]([NH:8][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)=[O:12])[OH:14]

Participants

5

Reactant 2

HCID 795054-Phenylsemicarbazide hydrochlorideHCID 3161902-(Hydroxyimino)-1H-indene-1,3(2H)-dione

Product 1

HCID 1363811582-Oximino-1-(4-phenyl semicarbazono)-3-indanone

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

0.01 mol of 4-phenyl semicarbazide hydrochloride in solution in 10 ml water was added to a solution of 0.01 mol of 2-oximino indan-1,3-dione in 60 ml ethanol. The reaction mixture was refluxed for 1 hour. The precipitate formed was centrifuged when hot, dried and recrystallised from acetonitrile.

Workup

  1. temperatureThe reaction mixture was refluxed for 1 hour
  2. customThe precipitate formed
  3. customdried
  4. customrecrystallised from acetonitrile

Sources & evidence

ORD record
ord-1778b1cf9298420f85defa4186ed0f03
Source dataset
uspto-grants-1997_07
Patent number
US05648381

Reaction notes

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