HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethyl phosphite → Diethyl 7-(2,4,5-triphenylimidazol-1-yl)heptane-phosphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethyl phosphite | HCID 31215 | — |
| Reactant | 1-(7-Bromoheptyl)-2,4,5-triphenylimidazole | HCID 22916377 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | Diethyl 7-(2,4,5-triphenylimidazol-1-yl)heptane-phosphonate | HCID 22916421 | 35% |
Reaction Steps
A mixture of 2,4,5-triphenyl-1-(7-bromoheptyl)-imidazole (0.95 g) and triethyl phosphite (1.66 g) in xylene (5 ml) was heated at reflux temperature for 20 hours. The mixture was evaporated to an oil and chromatographed on silica gel (ethyl acetate/ethanol) to give diethyl 7-(2,4,5-triphenylimidazol-1-yl)heptane-phosphonate (0.37 g, 35%) as a light brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05648373 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-b872718e0dee4eae9146f06ae2e83750 |
| Source note | uspto-grants-1997_07 |