反应详情

A mixture of 1,4,5-triphenylimidazol-2-one (6.25 g), dibromohexane (24.4 g) and potassium carbonate (5.53 g) in dry butanone (300 ml) was heated at reflux temperature for 24 hours. The mixture was cooled and the filtrate evaporated to an oil which was chromatographed on silica gel (hexane/ethyl acetate) to give 1,4,5-triphenyl-2-(6-bromohexyloxy)-imidazole (2.8 g, 29%) as a white solid, m.p. 87°-9° C.

1. temperaturewas heated
2. temperatureat reflux temperature for 24 hours
3. temperatureThe mixture was cooled
4. customthe filtrate evaporated to an oil which
5. customwas chromatographed on silica gel (hexane/ethyl acetate)