反应详情

Ethereal hydrogen chloride is added dropwise to a solution of 1.0 g. 1-(2-naphthoylmethyl)imidazole in 100 ml. anhydrous benzene until precipitation is complete. The product is filtered, washed with ether, air dried and recrystallized from methanol/acetone to yield 1-(2-naphthoylmethyl)imidazole hydrochloride, m.p. 226°-228.5° C. (decomp.)

1. customanhydrous benzene until precipitation
2. filtrationThe product is filtered
3. washwashed with ether, air
4. customdried
5. customrecrystallized from methanol/acetone