反应详情

温度

80 °C

A mixture of 1.7 g of 4-acetylamino-6-methyl-3-oxo-2,3,4,5-tetrahydro-1,2,4-triazine and 10 ml of 2N hydrochloric acid is stirred for 5 hours at 80° C. After cooling, 1.7 g of sodium acetate are added, and the mixture is concentrated by evaporation in vacuo at a bath temperature of 60° C. The residue is taken up in ethanol, and salt precipitates are filtered off. The filtrate is concentrated to a small volume and caused to crystallize. The title compound is obtained in the form of colorless crystals having a melting point of 116°-119° C.

1. temperatureAfter cooling
2. concentrationthe mixture is concentrated by evaporation in vacuo at a bath temperature of 60° C
3. customsalt precipitates
4. filtrationare filtered off
5. concentrationThe filtrate is concentrated to a small volume
6. customto crystallize