Hydrogen Peroxide → HCID 53799883, compound

HRID 265723Notes

Reaction equation

HRID 265723 reaction equation
S(=O)(=O)(O)O.[C:6]([N:14]1[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][C:15]1=[O:21])(=[O:13])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.[OH2:22].[OH:23]O>>[C:6]([NH:14][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][C:15]([O:21][OH:23])=[O:22])(=[O:13])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Participants

5

Reactant 4

HCID 784Hydrogen PeroxideHCID 962WaterHCID 1118Sulfuric AcidHCID 2244711-Benzoylazepan-2-one

Product 1

HCID 53799883HCID 53799883, compound

Conditions

Temperature
80 °C

Procedure

140 g of sulfuric acid are added dropwise in the course of half an hour to a liquid mixture of N-benzoyl-caprolactam (21.7 g, 100 mmol) and water (8.0 g, 440 mmol) at 68° C. The internal temperature increases in the course of this to 80° C., and the mixture is further stirred for 1 hour at this temperature. After the reaction solution is cooled to 20° C., 42 ml of 50% strength aqueous hydrogen peroxide solution are added dropwise. The internal temperature is kept between 25° and 30° C. during this by ice cooling. After one hour, the reaction batch is admixed with 500 ml of ice water, and the resulting colorless precipitate is filtered off by suction and washed to neutrality with water. Yield 22.2 g (88%), active oxygen content 6.2 % (98%).

Workup

  1. temperatureAfter the reaction solution is cooled to 20° C.
  2. customis kept between 25° and 30° C.
  3. waitAfter one hour
  4. filtrationthe resulting colorless precipitate is filtered off by suction
  5. washwashed

Sources & evidence

ORD record
ord-2e0234dbefca4dd6b4e8307f2435233c
Source dataset
uspto-grants-1997_07
Patent number
US05648521

Reaction notes

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