反应详情

温度

60 °C

A mixture of 24-2 (3.0 g, 12.4 mmol), 1N NaOH (30 mL), and ethanol was heated at 60° C. for 1.0 hour. The cooled reaction mixture was acidified with 10% KHSO4 and then extracted with EtOAc. The EtOAc portion was washed with brine, dried (MgSO4) and concentrated to give 24-3 as a white solid.

1. customThe cooled reaction mixture
2. extractionextracted with EtOAc
3. washThe EtOAc portion was washed with brine
4. dry with materialdried (MgSO4)
5. concentrationconcentrated