HRID265925

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID3017129

4-Phenylpiperidine-4-carboxamide monohydrochloride

C12H17ClN2O

结构：COc1cc(C(=O)N2CCC(CCCS(=O)(=O)[O-])(c3ccc4c(c3)OCO4)C2)cc(OC)c1OC

HCID86750913

未命名化合物

PRODUCTS

生成物

结构：COc1cc(C(=O)N2CCC(CCN3CCC(C(N)=O)(c4ccccc4)CC3)(c3ccc4c(c3)OCO4)C2)cc(OC)c1OC

HCID54440183

未命名化合物

PROCEDURE

实验过程

Prepare by the method of example 3.3 using 2-[3-(benzo[1,3]dioxol-5-yl)-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-ethyl-methanesulfonate (8 mmol) and 4-phenyl-piperidine-4-carboxylic acid amide hydrochloride (12 mmol). Chromatograph on silica gel to give the title compound.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f9251a58c1014a6fa18f522dadfc4725
来源数据集: uspto-grants-1997_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05648366
来源说明: uspto-grants-1997_07

反应 SMILES

[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]3([CH2:29][CH2:30]CS([O-])(=O)=O)[CH2:14][CH2:13][N:12]([C:15](=[O:28])[C:16]4[CH:21]=[C:20]([O:22][CH3:23])[C:19]([O:24][CH3:25])=[C:18]([O:26][CH3:27])[CH:17]=4)[CH2:11]3)=[CH:9][C:4]=2[O:3][CH2:2]1.Cl.[C:37]1([C:43]2([C:49]([NH2:51])=[O:50])[CH2:48][CH2:47][NH:46][CH2:45][CH2:44]2)[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1>>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]3([CH2:29][CH2:30][N:46]4[CH2:45][CH2:44][C:43]([C:37]5[CH:38]=[CH:39][CH:40]=[CH:41][CH:42]=5)([C:49]([NH2:51])=[O:50])[CH2:48][CH2:47]4)[CH2:14][CH2:13][N:12]([C:15](=[O:28])[C:16]4[CH:17]=[C:18]([O:26][CH3:27])[C:19]([O:24][CH3:25])=[C:20]([O:22][CH3:23])[CH:21]=4)[CH2:11]3)=[CH:9][C:4]=2[O:3][CH2:2]1