反应详情

Tri-o-thymotide (25 g) was dissolved in 2,2,4-trimethylpentane (50 ml) at 100° C. and the hot solution was introduced into the high pressure autoclave. Methyl bromide was added to the autoclave until a pressure of 200 bar was reached. The high pressure autoclave was then kept for 2 hours at 110° C. and the solution was then cooled down to room temperature within 5 days. The crystals were filtered off and washed 3 times with cold 2,2,4-trimethylpentane. The crystals were then dried in the drying cabinet at 50° C.

1. additionthe hot solution was introduced into the high pressure autoclave
2. filtrationThe crystals were filtered off
3. washwashed 3 times with cold 2,2,4-trimethylpentane
4. customThe crystals were then dried in the drying cabinet at 50° C.