反应详情

3.7 g of the product obtained in Example 1 were then introduced at ambient temperature and the mixture was stirred at ambient temperature for about 2 hours. Tetrahydrofuran with 20% water was introduced at a temperature of about 0° to 10° C., and the mixture was taken up in water, filtered, decanted and extracted with ethyl acetate. The organic phase was dried, filtered and the solvents were eliminated under reduced pressure at a temperature of about 50° C. to obtain 3.7 g of the expected product melting at <50° C.

1. filtrationfiltered
2. customdecanted
3. extractionextracted with ethyl acetate
4. customThe organic phase was dried
5. filtrationfiltered
6. customwere eliminated under reduced pressure at a temperature of about 50° C.