反应详情

Conc. sulfuric acid was added to a mixture of 2-amino-4,5,3',4'-tetramethoxybenzophenone, butyl acetoacetate and acetic acid. The mixture was treated according to the same manner as in Reference Example 1 to give butyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-methylquinoline-3-carboxylate (53%). This compound was recrystallized from ethyl acetatehexane. Colorless prisms, mp. 119°-120° C.

1. additionThe mixture was treated