HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → Butyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-methylquinoline-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Butyl acetoacetate | HCID 11576 | — |
| Reactant | 2-Amino-4,5,3',4'-tetramethoxybenzophenone | HCID 9926967 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Butyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-methylquinoline-3-carboxylate | HCID 21851183 | 53% |
Reaction Steps
Conc. sulfuric acid was added to a mixture of 2-amino-4,5,3',4'-tetramethoxybenzophenone, butyl acetoacetate and acetic acid. The mixture was treated according to the same manner as in Reference Example 1 to give butyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-methylquinoline-3-carboxylate (53%). This compound was recrystallized from ethyl acetatehexane. Colorless prisms, mp. 119°-120° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05650410 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-8e87e3bd256f4d09a22446560010d74f |
| Source note | uspto-grants-1997_07 |