反应详情

A mixture of benzyl 4-(N,N-diethylamino)butanoate (33.8 g), palladium-carbon (5%, 7 g) and ethanol (500 ml) was subjected to catalytic hydrogenation at room temperature and 1 atm. The catalyst was filtered off, and the filtrate was concentrated under reduced pressure to give 4-(N,N-diethylamino)butanoic acid (16.2 g, 75%). mp. 45°-47° C.

1. customwas subjected to catalytic hydrogenation at room temperature
2. filtrationThe catalyst was filtered off
3. concentrationthe filtrate was concentrated under reduced pressure