HuagongsheHuagongshe Chemistry Print Report · For research reference only
benzyl 4-(N,N-diethylamino)butanoate → Butyric acid, 4-(diethylamino)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | benzyl 4-(N,N-diethylamino)butanoate | HCID 19032368 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Butyric acid, 4-(diethylamino)- | HCID 44844 | 75.1% |
Reaction Steps
A mixture of benzyl 4-(N,N-diethylamino)butanoate (33.8 g), palladium-carbon (5%, 7 g) and ethanol (500 ml) was subjected to catalytic hydrogenation at room temperature and 1 atm. The catalyst was filtered off, and the filtrate was concentrated under reduced pressure to give 4-(N,N-diethylamino)butanoic acid (16.2 g, 75%). mp. 45°-47° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05650410 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-202be315fad54cc1b36e00ad8c2182b2 |
| Source note | uspto-grants-1997_07 |