Diethylamine → HCID 54168925, compound

HRID 266143Notes

Reaction equation

HRID 266143 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([CH2:12]Cl)[C:6]([C:14]([O:16][CH2:17][CH3:18])=[O:15])=[C:5]2[C:19]1[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][CH:20]=1.[CH2:26]([NH:28][CH2:29][CH3:30])[CH3:27]>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([CH2:12][N:28]([CH2:29][CH3:30])[CH2:26][CH3:27])[C:6]([C:14]([O:16][CH2:17][CH3:18])=[O:15])=[C:5]2[C:19]1[CH:20]=[CH:21][C:22]([Cl:25])=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 8021DiethylamineHCID 22097636HCID 22097636, compound

Product 1

HCID 54168925HCID 54168925, compound

Procedure

According to the same manner as that described in Example 33, ethyl 6-chloro-2-chloromethyl-4-(4-chlorophenyl)quinoline-3-carboxylate was reacted with diethylamine to give ethyl 6-chloro-4-(4-chlorophenyl)-2-(N,N-diethylaminomethyl)quinoline-3-carboxylate. This compound was recrystallized from ethanol. Colorless prisms, mp. 132°-133° C.

Sources & evidence

ORD record
ord-a26002dd514f4784830d13db161fbee7
Source dataset
uspto-grants-1997_07
Patent number
US05650410

Reaction notes

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