HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl 7-(N,N-diethylamino)-3-oxoheptanoate → ethyl 2-[4-(N,N-diethylamino)butyl]-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinoline-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl 7-(N,N-diethylamino)-3-oxoheptanoate | HCID 19032365 | — |
| Reactant | 2-Amino-3',4',4,5-tetramethoxybenzophenone hydrochloride | HCID 21466134 | — |
| Product | ethyl 2-[4-(N,N-diethylamino)butyl]-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinoline-3-carboxylate | HCID 19032373 | — |
Reaction Steps
According to the same manner as that described in Example 49, 2-amino-4,5,3',4'-tetramethoxybenzophenone hydrochloride was reacted with ethyl 7-(N,N-diethylamino)-3-oxoheptanoate to give ethyl 2-[4-(N,N-diethylamino)butyl]-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinoline-3-carboxylate. This compound was recrystallized from ethyl acetate - hexane. Colorless prisms, mp. 171°-172° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05650410 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-410955bb2e194b22bc233967dd45ed34 |
| Source note | uspto-grants-1997_07 |