Dicyclohexylcarbodiimide → 2-Dimethylaminopyridine

HRID 266196Notes

Reaction equation

HRID 266196 reaction equation
[CH3:1][C@H]1OC(=O)C2C(O)=CC(O)=C(Cl)C=2CC(=O)C=CC=C[C@H]2O[C@H]2C1.COCOCCCCCCCCCC(O)=O.[CH:42]1([N:48]=[C:49]=[N:50][CH:51]2[CH2:56][CH2:55][CH2:54]CC2)CCCCC1>O1CCCC1>[CH3:1][N:48]([C:49]1[CH:54]=[CH:55][CH:56]=[CH:51][N:50]=1)[CH3:42]

Participants

5

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 11268547CID 11268547HCID 19032994HCID 19032994, compound

Product 1

HCID 218852-Dimethylaminopyridine

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following a procedure similar to that described in Example 12, but using 400 mg of radicicol, 595 mg of 10-(methoxymethoxy)decanoic acid, 6 ml of dry tetrahydrofuran, 567 mg of dicyclohexylcarbodiimide and a catalytic amount of dimethylaminopyridine, 739 mg of the title compound were obtained.

Sources & evidence

ORD record
ord-fdd14351b5bf4cbdb21223fb70b8b14b
Source dataset
uspto-grants-1997_07
Patent number
US05650430

Reaction notes

Loading…