Dicyclohexylcarbodiimide → 2-Dimethylaminopyridine

HRID 266197Notes

Reaction equation

HRID 266197 reaction equation
[CH3:1][C@H]1OC(=O)C2C(O)=CC(O)=C(Cl)C=2CC(=O)C=CC=C[C@H]2O[C@H]2C1.COCCOCOCCCCCCCCCCCC(O)=O.[CH:47]1([N:53]=[C:54]=[N:55][CH:56]2[CH2:61][CH2:60][CH2:59]CC2)CCCCC1>O1CCCC1>[CH3:1][N:53]([C:54]1[CH:59]=[CH:60][CH:61]=[CH:56][N:55]=1)[CH3:47]

Participants

5

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 11268547CID 11268547HCID 54479626HCID 54479626, compound

Product 1

HCID 218852-Dimethylaminopyridine

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following a procedure similar to that described in Example 12, but using 400 mg of radicicol, 856 mg of 12-(methoxyethoxymethoxy)dodecanoic acid, 6 ml of dry tetrahydrofuran, 567 mg of dicyclohexylcarbodiimide and a catalytic amount of dimethylaminopyridine, 893 mg of the title compound were obtained.

Sources & evidence

ORD record
ord-1c8b6e7f0c8846e59893f2c703de6d0b
Source dataset
uspto-grants-1997_07
Patent number
US05650430

Reaction notes

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