Dicyclohexylcarbodiimide → 2-Dimethylaminopyridine

HRID 266199Notes

Reaction equation

HRID 266199 reaction equation
[CH3:1][C@H]1OC(=O)C2C(O)=CC(O)=C(Cl)C=2CC(=O)C=CC=C[C@H]2O[C@H]2C1.COCCOCOCCCCCCCCCCCCCCCC(O)=O.[CH:51]1([N:57]=[C:58]=[N:59][CH:60]2[CH2:65][CH2:64][CH2:63]CC2)CCCCC1>O1CCCC1>[CH3:1][N:57]([C:58]1[CH:63]=[CH:64][CH:65]=[CH:60][N:59]=1)[CH3:51]

Participants

5

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 11268547CID 11268547HCID 54053292HCID 54053292, compound

Product 1

HCID 218852-Dimethylaminopyridine

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following a procedure similar to that described in Example 12, but using 400 mg of radicicol, 996 mg of 16-(methoxyethoxymethoxy)hexadecanoic acid, 6 ml of dry tetrahydrofuran, 567 mg of dicyclohexylcarbodiimide and a catalytic amount of dimethylaminopyridine, 946 mg of the title compound were obtained.

Sources & evidence

ORD record
ord-c95b5e6a36514cdc9334354d03fd44b8
Source dataset
uspto-grants-1997_07
Patent number
US05650430

Reaction notes

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