Phenylboronic Acid → 3-Cyclopentyloxy-4-methoxy-biphenyl

HRID 266203Notes

Reaction equation

HRID 266203 reaction equation
[C:1]1(B(O)O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:10]1([O:15][C:16]2[CH:17]=[C:18](Br)[CH:19]=[CH:20][C:21]=2[O:22][CH3:23])[CH2:14][CH2:13][CH2:12][CH2:11]1>>[CH:10]1([O:15][C:16]2[CH:17]=[C:18]([C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)[CH:19]=[CH:20][C:21]=2[O:22][CH3:23])[CH2:14][CH2:13][CH2:12][CH2:11]1

Participants

3

Reactant 2

HCID 66827Phenylboronic AcidHCID 99703924-Bromo-2-(cyclopentyloxy)-1-methoxybenzene

Product 1

HCID 214727683-Cyclopentyloxy-4-methoxy-biphenylYield 46%

Procedure

Following the procedure of Example 1, phenylboronic acid and 3-cyclopentyloxy-4-methoxybromobenzene yielded 46% of the title compound as white needles: mp 62°-64° C.

Sources & evidence

ORD record
ord-d7887de0c94149fd8836d030159cd63d
Source dataset
uspto-grants-1997_07
Patent number
US05650444

Reaction notes

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