HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 266475Generated: October 27, 2026
Methyl iodide → 2-Benzyl-4-ethoxy-6-allyl-7-methoxysaccharin
https://huagongshe.com/reaction/266475
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Benzyl-4-ethoxy-6-allyl-7-hydroxysaccharin | HCID 70053082 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 2-Benzyl-4-ethoxy-6-allyl-7-methoxysaccharin | HCID 70051638 | 92% |
Reaction Steps
A mixture of 2-benzyl-4-ethoxy-6-allyl-7-hydroxysaccharin (2.45 g), potassium carbonate (2.76 g) and methyl iodide (1.84 g) in acetone was heated at 50° C. with stirring for two hours, then poured with stirring into ice-water (500 mL). The resulting gooey precipitate crystallized overnight affording 2-benzyl-4-ethoxy-6-allyl-7-methoxysaccharin, 2.35 g, 92% yield, mp 92°-94° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05650422 |
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| Source dataset | uspto-grants-1997_07 |
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| ORD ID | ord-e9083ac3e1644147b861fef8130daa4c |
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| Source note | uspto-grants-1997_07 |
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