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HRID266477

反应详情

EQUATION

反应方程式

HRID 266477 的结构方程式

REACTANTS

反应物

2
结构：O=S(=O)(Cl)Cl
HCID24648

Sulfuryl chloride

Cl2O2S

结构：CCCc1cc(OCC)c2c(c1OC)S(=O)(=O)N(CSc1ccccc1)C2=O
HCID70050453

未命名化合物

PRODUCTS

生成物

1
结构：CCCc1cc(OCC)c2c(c1OC)S(=O)(=O)N(CCl)C2=O
HCID70050498

未命名化合物

收率 89%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

By the method of part E of Example 45 2-phenylthiomethyl-4-ethoxy-6-propyl-7-methoxysaccharin (0.85 g) was reacted with sulfuryl chloride (0.30 g) in dichloromethane and purified with hexane affording 2-chloromethyl-4-ethoxy-6-propyl-7-methoxysaccharin, 0.62 g, 89% yield, mp 131°-133° C.

WORKUP

后处理

  1. custompurified with hexane