HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuryl chloride → 2-Chloromethyl-4-ethoxy-6-propyl-7-methoxysaccharin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | 2-Phenylthiomethyl-4-ethoxy-6-propyl-7-methoxysaccharin | HCID 70050453 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Chloromethyl-4-ethoxy-6-propyl-7-methoxysaccharin | HCID 70050498 | 89% |
Reaction Steps
By the method of part E of Example 45 2-phenylthiomethyl-4-ethoxy-6-propyl-7-methoxysaccharin (0.85 g) was reacted with sulfuryl chloride (0.30 g) in dichloromethane and purified with hexane affording 2-chloromethyl-4-ethoxy-6-propyl-7-methoxysaccharin, 0.62 g, 89% yield, mp 131°-133° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05650422 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-878ea74f98944296818a6a0e26d276c4 |
| Source note | uspto-grants-1997_07 |